Supramolecular Impact Assessment in Microscopic In Vivo Model Systems
Biological and Logistical Alternatives to Vertebrate Animal Experimentation
If you are looking for a fast, relevant, and cost-effective solution to assess the effects of any molecule, solution, extract, or treatment, the renaissance approach of Micro-InVivo® (MIV) offers an ideal and ethically preferable alternative. This innovative research platform provides unique capabilities that, to a significant extent, can substitute for the highly expensive and cumbersome vertebrate animal models (in vivo) as well as cell- and tissue culture systems (in vitro). In contrast to in vitro and some in vivo systems, the MIV is able to measure particulate, coagulation, flocculation, micellar, and colloidal active agents that are either insoluble or only slightly soluble in water.
The multispecies MIV model and testing system embody a childhood dream brought to life. The world of microscopic animals, with its diversity and dimensions, offers uniquely advantageous alternatives to the practical needs, gaps, and perspectives encountered in a researcher's career. Our goal is to elevate this repertoire to a professional level in the form of the MIV system.
Molecular biology has revolutionized scientific understanding. However, comprehending the intricacies of supramolecular interactions and living systems remains crucial for groundbreaking discoveries. In vivo models, especially MIV systems, are essential for this comprehensive approach, enabling efficient and rapid drug discovery and opening new avenues for fundamental research.
1. What is MIV?
MIV represents a novel approach that bridges the translational gap between in vitro, ex vivo and in vivo studies, offering enhanced efficiency and minimal experimental compromise. As a laboratory research, development, and innovation tool, our service fills a previously missing link in the methodological palette of laboratory research. It is a groundbreaking testing system that bridges the gap between cell cultures and rodent models, utilizing real, miniature entities.
2. What makes MIV globally unique?
We utilize high-throughput screening (HTS) in vivo test and model systems based on microscopic invertebrates (e.g., Rotifera, Stenostomidae, Nematoda), which are not subject to ethical restrictions. This unique approach provides the speed and scalability of cell cultures combined with the biological relevance of vertebrate animals, offering researchers a powerful new tool for discovery. We pride ourselves on our agility and responsiveness, adapting to emerging professional needs and unique research ideas with exceptional speed – both in theory and in practice.
Consider
using our relevant microscopic in vivo (micrometazoan) model system
to test and
screen your active compounds before, instead of, or in parallel
as a complement
to macroscopic in vivo (mollusks, vertebrate, mammalian) testing.
3. What are the professional benefits of using the MIV system?
Before embarking on classic mouse/rat/etc. experiments, test with us! Our system allows you to quickly gather essential data on a range of parameters, including toxicity, aging and lifespan, survival rates, metabolic processes, exogenous secretion, drug responses, and gene expression. This data, often time-consuming and costly to obtain using traditional vertebrate models, can be acquired rapidly and cost-effectively with MIV. Our in vivo system facilitates both endpoint-free and long-term monitoring, allowing you to track a wide array of parameters, from overall lifespan to specific cellular processes like autophagy.
4. What is the translational value of the MIV animal model system for vertebrates?
One of the key advantages of the MIV system is its high translational relevance to vertebrates. This means that findings from studies using our microscopic animal models can be reliably applied to understanding biological processes in higher organisms, including humans. For example, MIV models have been successfully used to study the effects of aging on mitochondrial function, screen for new drug candidates targeting specific metabolic pathways, and investigate the mechanisms of neurodegenerative diseases. We utilize advanced genome-based analysis to ensure the relevance of our models to specific vertebrate species. This enables researchers to translate findings from MIV studies to their target organisms confidently.
To ensure the biological relevance of the MIV system, various micrometazoan species
are
applied simultaneously during the testing of a given
active compound
5. Is it worth choosing and trying MIV?
Certainly. The MIV represents a globally unparalleled, sophisticated system, the result of several years of development by professionals with extensive experience. The efficacy and innovation of invivomics applications have been substantiated by multiple prestigious international publications authored by our team. We guarantee both superior quality and exceptional efficiency.